Characterization of prethymic progenitors within the chicken embryo

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Characterization of prethymic progenitors within the chicken embryo.

The thymic primordium in both birds and mammals is first colonized by cells emerging from the intra-embryonic mesenchyme but the nature of these precursors is poorly understood. We demonstrate here an early embryonic day 7 prethymic population with T lymphoid potential. Our work is a phenotypic analysis of, to date, the earliest embryonic prethymic progenitors arising in the avian para-aortic a...

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During murine fetal development, hematopoietic progenitors start to colonize the thymic anlage at day 11 of gestation via blood stream. The present study aims at identifying the earliest prethymic progenitors in circulation. Here, we show that the IL-7R cells in Linc-kit population are circulating exclusively between days 11 to 14 of fetal age. Clonal analysis revealed that these IL-7R cells mo...

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Identification of the earliest prethymic T-cell progenitors in murine fetal blood.

During murine fetal development, hemato-poietic progenitors start to colonize the thymic anlage at day 11 of gestation via blood stream. The present study aims at identifying the earliest prethymic progenitors in circulation. Here, we show that the interleukin-7 receptor-positive (IL-7R+) cells in Lin- c-kit+ population are circulating exclusively between days 11 and 14 of fetal age. Clonal ana...

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ژورنال

عنوان ژورنال: International Immunology

سال: 1999

ISSN: 1460-2377,0953-8178

DOI: 10.1093/intimm/11.1.63